Talking Hormones, Longevity, and the Science of Thriving

From podcasts and panels to press features and bylines, I’m on a mission to make hormones, longevity, and sexual health part of our everyday conversations.

The Conversations I Keep Coming Back To

Women’s longevity
Menopause & perimenopause (including the Perimenopause Glass Ceiling)
Hormone optimization therapy in women
“SEXponential” health, the surprising relationship between sexual wellness and healthspan
Regenerative medicine (stem cells, exosomes) & advanced clinical therapies

Featured Podcasts

Also Seen On:

The Human Upgrade: Biohacking for Longevity & Performance with Dave Asprey
Boundless Life with Ben Greenfield
Digital Social Hour with Sean Kelly
The Dr. Hyman Show
The Mindvalley Podcast with Vishen Lakhiani
The mindbodygreen Podcast
Be Well by Kelly Leveque

The Broken Brain
Siim Land Podcast
Meisha Tate
The NORMAKAMALIFE podcast
The Resetter Podcast with Dr. Mindy Pelz
Metabolic Freedom With Ben Azadi
Built for Growth by Miesha Tate

Featured Articles

Also Featured In...

Get in Touch

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Feb 3

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Wondering where to apply testosterone cream or gel? 🤔

Aim for 3 things ...
🔺 Low sebaceous and sweat glands
🔺 Low androgen-responding hair follicles
🔺 Low risk of transference to kids/pets

Want more info? This week's (free) Substack has 10 Testosterone Tips and Tricks that you probably don't know (but should).

Comment "SUBSTACK" for a link. 👇

What's your favorite place to put testosterone?

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Feb 2

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😱 Does testosterone for women scare you?
It shouldn't!

❌ It's not just for men
❌ It's not illegal
❌ It's not turning you into a bodybuilder

But like all good things, the details matter.
📣I've rounded up my best tips & tricks to help you maximize the benefits of this powerful hormone!

Comment "SUBSTACK" to get this week's free article sent right to you!

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Feb 1

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All adult V@ginas Need Estrogen! 🌺

If you don't make it ... Take it!

Low dose vaginal estrogen is CHEAP. You only need 2-3 grams a week so this $35 tube from GoodRx or will last a couple of months.

Cost Plus Drugs has the same thing for $13. No insurance needed. 😍

You do need a prescription (sadly) but it's incredibly beneficial and extremely safe (even for BC survivors).

I wish I'd invented it myself but, alas, I did not.

😘

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Jan 30

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🦴 Did you know you can build your bones?
Yep, it's true!

😎 Estrogen can help women prevent bone loss and even rebuild your bones.
Swipe to see your questions answered.

To learn more, check out my Substack article called "Bon Appetit"

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Jan 29

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Does size matter? 🤔

When it comes to your estrogen dose and bone building... Yes!

Low dose estrogen can help prevent bone loss but higher doses are needed for bone building.

What do you think? Does size matter? ❓

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Jan 26

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Need help with sleep? 🤔

Oral progesterone can be great for many women. ✅

Of course, estrogen too if night sweats are a problem.

And I also like things like L-Theanine, Magnesium Glycinate, Glycine, and Melatonin.

What's your favorite sleepy time helper? ❓

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Jan 25

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This song is called "Not Mad Enough" by Smith and Myers.

Says enough.

- Amy

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Jan 23

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Estriol = Weak sauce. 😏

Bi-Est = Estriol + Estradiol

Biest isn't dangerous but I don't find it any safer or more useful than plain estradiol.

Estriol 0.3% is a common concentration used for localized treatment of skin and pelvic floor.

Have you used Biest? What's your experience been? ❓

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Jan 22

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🩸 Ancient Egypt blamed “old blood.”
💦 Rome prescribed bull urine.
🧙‍♀️ The Middle Ages said “witch.”
👨‍⚕️ Modern medicine said… “eh, just deal with it.”

Let’s talk about the chaotic history of HRT and why the tide is finally turning.

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Jan 21

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Medical Providers and Hormone Zealots! 💥

If you want to learn how to safely prescribe hormones by someone who's been doing it for 13+ years, my Hormone Optimization Therapy (HOT) course is for you!

This course focuses on female hormones, but we also cover male hormones and thyroid.

Comment "HOT COURSE" for a link to the website to learn more. ✅

And thanks to my early adopters and testimonial-givers... @catherinejohnsonmd @sandikrakowski

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Jan 20

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😬Sometimes “bioidentical” hormones are not the hero of the story.
🚨Before the hormone police revoke my license—hear me out.

Medicine isn’t a religion. Estradiol + progesterone are usually great… but not always.
👉I’m breaking down 4 situations where bioidentical is just not enough,
And what I'd suggest in place.

Comment "SUBSTACK" for this week's read!

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Jan 19

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Taking testosterone therapy? 🤔

Although benefits can start within a month, they often take 3-6 months to fully manifest.

Similarly, side effects (ex: acne, body/face hair growth, scalp hair loss) often take 3+ months to begin. 😏

This is why we wait AT LEAST 3 months before we increase your testosterone dose.

And, if you're cutting back or stopping testosterone, know that it may be another 3-6 months for side effects to resolve. 😡

Have you had side effects on T? ❓❓

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Jan 18

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We don't dose your thyroid meds by asking for a vibe check. 💥

We don't give you blood pressure medication and say, "Just take whatever makes you feel good"

And yet we tell women to ONLY use symptoms to guide their menopause hormone therapy dosing.

We tell women there's no specific effective dose. Don't worry about lab testing. 😡

This is wrong. Yes, trust your feelings. Yes, symptom matters significantly. But also ... If we want to use hormones to effectively prevent future diseases like osteoporosis, heart disease, and metabolic syndrome then we need objective measures.

Data > Vibes ✅

P.S. Several months ago I wrote a Substack article on what I consider optimal serum estradiol for most women. Comment "Substack" for a link then scroll to "Why won't anybody tell me what my optimal estradiol should be?"

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Jan 16

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Two for one estrogen? 🤔

Low dose vaginal estradial can be used on the face as well as the v@gina/vulva.

You should discuss dosing with your physician to avoid getting too much (especially if you're not taking progesterone) but a little dab to both places is well tolerated by many women. ✅

Some women prefer to get their low-dose estradiol compounded with things like hyaluronic acid, GHK-Cu or natural oils for a less "ointment-y" feel on the face.

But, for those on a budget (or just lazy like me!) the pharmaceutical estradiol 0.01% cream works well (but does require a prescription). 🥳

Have you tried this trick? ❓

Share with a friend who needs this! 🥂

@young_goose_skincare

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Jan 15

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🚫 Not all HRT is created equal.
Before you fill the prescription, ask these 3 questions.

📲 Save this—you’ll want it later.

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Jan 14

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Airport security made me think about the immune system, which reminded me of its role in inflammation, which took me back to a recent podcast, which resulted in me doing a spontaneous mid-airport monologue. ✈️

Which caused a few people to stare but, not as many as you'd think. 🤣

Welcome to my life. 😃

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Jan 13

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It's time to stop scaring women! 💥

Yes, BRCA gene variants increase the risk of ovarian and breast cancer.

But taking hormone therapy after removal of the ovaries does NOT seem to increase breast cancer risk. ‼️

My Substack this week breaks down this study, as well as what was previously known in this topic.

What other myths about hormones should we bust? ❓

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Jan 12

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⁉️ What if the thing you were told to fear…
Was never the problem?

🤔 New research shows hormone therapy does not increase breast cancer risk in BRCA carriers
And estrogen may even be protective.

So why are women still being told no?
I break down the latest research and the unknowns.
Comment "SUBSTACK" to get this sent right to you!

Study: JNCI: Journal of the National Cancer Institute, djaf363, https://doi.org/10.1093/jnci/djaf363

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Jan 11

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Low dose vaginal estrogen is safe, even in women with a history of hormone sensitive cancer. 💪

The estrogen considered "low dose* is 10-100 mcg per dose and can be taken as a vaginal suppository (ex: Vagifem), ring (Estring), or cream (estradiol 0.01%).
.
Vaginal estrogen can reduce recurring UTIs significantly (among other things). 💃

It's never to late to start it and it's an extremely safe wonder drug! ✅

What's your favorite way to take vaginal estrogen? ❓

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Jan 9

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Want to learn about prescribing Hormone Optimization Therapy (HOT)? ❓

My HOT Provider course is finally finished! 💃

If you're a medical provider or someone who takes care of women in midlife, this course is for you!

I also cover men's hormones so you'll be ready for anything that walks through your door!

Comment "HOT COURSE" below for a link or visit dramykillen.thinkific.com. 👇

Let's Go! 🥳

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