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May 7

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Is your v@gina in the "top 1%"?

While I don't think we necessarily need to rate the quality of our lady-parts and publish to social media, I do appreciate that @bryanjohnson_ and his girlfriend @katetolo have opened up about an important topic - vaginal microbiome health.

At perimenopause/menopause, shifts in estrogen change the vaginal pH and microbiome, making infections more likely. 😏

Adding estrogen back in the form of low dose vaginal estrogen is Step 1. 💪

Vaginal microbiome testing is not standard of care currently but it's something I'd consider in someone with recurring infections or discomfort.

What do you think? Was his post educational or a bit of an over-share? ⁉️

P.S. I do not have a financial relationship with any vaginal microbiome testing company or any vaginal probiotic company. ❎

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May 6

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Sexual health is health. 💥

It gets input from all of the other types of health.

A healthy sex life also has multiple benefits, including improvements in emotional and cognitive health, blood pressure, sleep, and immune system.

This is why sex is so strongly correlated with increased lifespan.

What do you think? ⁉️

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May 5

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A woman's life on hormones... Three surprises. 💥

1) Testosterone peaks at 25 and slowly declines. It does NOT markedly decline at menopause like estradiol and progesterone.

2) Progesterone is 15-30 times higher (on average) than testosterone and 50-100 times higher than estrogen.

3) Testosterone is 2-4+ times higher than estrogen.

Remember these things when you think about replacing hormones in midlife!

What surprised you most? ⁉️

P.S. I swear I don't really have a mustache. Idk what's going on here. Please ignore. 😩

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May 2

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We did it! 🎉

One whirlwind day in NYC with the fabulous team from @lancomeofficial for the official U.S. launch of #absoluelongevityMD .

Four doctors, all from very different specialists.

And a team of make-up artists and hair stylists!

Thanks to @drdavidluu and my #girlsquad - @tiffanymoonmd and @drgabriellelyon for making this whole thing so fun!

Now... Excuse me as I go hide out for a week ! 😏

⚡ Makeup by @bobscott200 , Hair by @kabutohair

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May 1

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Do you want to understand how to prescribe hormones? 👍

<7% of medical providers feel comfortable treating menopausal women.

I've been treating men and women with body-identical hormones since 2013. I've taken many courses and treated thousands of men and women.

I created the HOT Provider course for people wanting an evidence-based curriculum that goes well beyond current guidelines.

This course includes 22+ videos, a 300+ page guidebook, and cheat sheets for hormone optimization in men and women. 😍

Want a free taste? Get my HOT Provider Quick Start Guide by commenting "QUICK START" below. 👇

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Apr 30

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It's the big day! 💥

"Man on Fire" comes out today on @netflix !

My husband @killen8 is the writer/creator and the fabulous @yahya is the lead actor.

No, it's not about hormones. But, surely we have other interests around here?! 😏

Grab a friend and give it a watch. We want Netflix to pick it up for another season.

Who's gonna watch? ⁉️

P.S. The inclusion of certain doctors in this video does not imply their endorsement and no money exchanged hands. They are just there to ask some much-needed questions! 🤣

@drmaryclaire
@drvondawright
@jessicashepherdmd
@nataliecrawfordmd
@drrachelrubin
@kellycaspersonmd
@joshuagonzalezmd

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Apr 29

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What if you could choose your skin's age? 💥

As a member of @lancomeofficial Longevity MD Advisory Board I've gotten to see first-hand the concepts we hold dear in longevity medicine getting applied to skincare.

Their Absolue Longevity MD product line features Urolithin-A by @timeline_longevity - a potent postbiotic supporting mitochondrial health.

Targeting the biological aging signs BEFORE they appear is a lofty goal but I have full faith that the Absolue Longevity MD product line is up for the task!

Who's ready to give it a try? ⁉️

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Apr 29

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Sexual health for the win! 🎉

In men, frequency of sexual activity and org@sm are directly associated with lifespan.

And, men with a low libido had higher mortality rates in one Japanese study, even after controlling for confounders like cardiovascular disease, smoking, BMI, marital status, and even frequency of laughter. 😆

These studies show correlation, not causation, but they're a good reminder that libido and sexual health are biomarkers of health - just like blood pressure and lean muscle mass.

In women, some studies show correlations between sexual frequency and longevity, but the relationship is more complex. Women benefit more from GOOD sex than just BLEH sex. ✅

What do you think about these studiea?❓ Share this message with someone who needs to hear it.😘

P.S. Thanks to @abundancesummit and @peterdiamandis for letting me speak on the big stage at Abundance Summit 2026. 🙏

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Apr 28

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Oops. I accidentally started a supplement company. 🥺

HOP Box is 19 ingredients in five pills, taken twice daily, designed by me to address the underlying drivers of aging in women.

We're underway with our first clinical study on midlife women and are SO EXCITED to share more soon. 💥

Want to give it a try?

Use the code"FRIENDSOFAMY" for 35% off the first month of your HOP Box subscription. ✅

This limited time deal is available at www.hopbox.life. 🥰

Xoxo....Amy

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Apr 27

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When a man can't get an erection, his doctor checks his
heart. When a woman can't get aroused or sensation changes, she's told to
relax. 😲

Same arteries. Same biology. Wildly different
medicine.

Female sexual dysfunction may be an even earlier warning sign
of cardiovascular disease than erectile dysfunction.
The
clitoral artery is 0.9 mm — smaller than the penile artery,
smaller than the coronary artery. Smallest pipes fail first.

But there's no guideline telling doctors to check. ❎

This is Part 3 of my "Lies You Were Told About the Land Down
Under" series.

Full article on Substack — comment SUBSTACK and
I'll send you the link. 👇

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Apr 25

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No......

Estrogen does not increase mortality rates from any cause (including breast cancer). 💥

Testosterone therapy does not increase heart disease, breast cancer, blood clots or cause irreparable harm when dosed correctly. ♥️

Transdermal estradiol does not increase blood clot risk in ANY study. 🥳

And... Avoiding the sun does not make you healthier, happier or longer living. 🌞

What medical myths is it time to reexamine? ⁉️

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Apr 23

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Estradiol + GLP-1 meds for the win! 💥

Estradiol has direct effects on secretion of GLP-1 from your body.

Estradiol also up-regulates brain GLP-1 receptors and improves responsiveness to GLP-1 in the brain. 🧠

Estradiol and GLP-1 also work synergistically on metabolic factors like visceral fat, blood sugar and inflammation.

In studies, menopausal women on GLP-1s and HRT saw 20-30% improvements in weight loss compared to women taking GLP-1s alone. 💥

Have you combined these two powerfully medications? ⁉️

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Apr 22

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Osteoporosis/osteopenia is reversible!

Normal bone density by DEXA is above -1.0.
Osteopenia is -1.0 to -2.5
Osteoporosis is below -2.5.

My mom's recent DEXA scan's lowest T score was -1.1. She's ,79 yo and has been working hard to reverse bone loss, including...

🔺Eating 100 g/ day of protein
🔺 Getting 1200 mg of calcium (mostly from food)
🔺 Getting 2000-5000 IU/day of Vitamin D3 + K2
🔺 Taking magnesium and creatine
🔺 Resistance training at home or the gym most days.
🔺 Prioritizing sleep, stress reduction, and healthy food.
🔺 Taking estradiol daily

I'm proud of her. You can do it too! 💪

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Apr 21

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Your hormones affect EVERYTHING!

Including how fast you metabolize caffeine. ☕

Estrogen and progesterone influence how quickly your liver metabolizes caffeine.

Lack of hormones in menopause can slow metabolism, making caffeine stick around longer.

Oral contraceptives and pregnancy and also slow caffeine break-down. 🥺

During your cycle, caffeine metabolism is slowest when estrogen peaks, just before ovulation.

Have you noticed changes in how caffeine affects your sleep, mood, or other symptoms recently? ⁉️

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Apr 20

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The ovaries are the pacemakers of healthy aging in women. 🔬

I just got back from a Berkeley symposium (QB3) where scientists shared research that
will change how you think about your body — your ovaries shape your brain, your
heart, your immune system and your lifespan long before (peri)menopause begins.

Swipe through for 5 wild discoveries, then head to my Substack for the full story.

Which one surprised you the most? ⁉️

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Apr 19

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Fun weekend in SF at the @livelong_media women's health summit. 💥

My session was on The Ozempic Era and you guys showed up! We got so many questions, which was awesome!

I have no pictures from the stage but I was lucky enough to run into many of my friends, aka... The Who's Who of Women's health. 🔥

And, if you missed my IG Stories, I had QUITE a hilarious/bizarre SF hotel/hostel situation (that may or may not have involved me finding a large Magic Wand in the desk drawer where the hair dryer should have been). 🪄

Were you there? Did you enjoy the event? ⁉️

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Apr 17

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Women live longer in every society, in every era, all across the world. 💥

Yes, we spend a few more years in poor health compared to men but that doesn't take away from the fact that we have protections built in.

Our XX chromosomes contribute. Partially because so many immune genes live there (and we've got two copies).

And our ovaries offer us huge protections. 💪

For the last few years I've studied female longevity to try to understand both our superpowers and our vulnerabilities.

What do you think are reasons that women typically live longer? What are our biggest longevity superpowers? ⁉️

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Apr 16

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You don't have to have low testosterone on your blood test to benefit from testosterone therapy. 🥺

Women with normal range testosterone who have symptoms of low testosterone, especially sexual symptoms, still benefit from therapy.

Classic low T symptoms include low desire, arousal problems, org@smic problems. ✅

Less classic (and less studied) symptoms include low motivation, fatigue, brain fog, difficulty forming muscle, difficulty making decisions.

Have you tried testosterone therapy? What were the effects? ⁉️

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Apr 15

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The ovaries are the pacemakers of healthy aging.

Today I attended the QB3

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Apr 13

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